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Alpha-Adrenergic Agents Antihypertensive effect of alpha-adrenergic blockers such as guanethidine, betanidine, reserpine, alpha-methyldopa or clonidine may be potentiated by beta-blockers including Lopressor. Beta- adrenergic blockers may also potentiate the postural hypotensive effect of the first dose of prazosin, probably by preventing reflex tachycardia.
- Diabetes And Hypoglycemia Beta blockers may mask tachycardia occurring with hypoglycemia, but other manifestations such as dizziness and sweating may not be significantly affected.
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- Lopressor showed effects on spermatogenesis in male rats at a therapeutic dose level, but had no effect on rates of conception at higher doses in animal fertility studies see Carcinogenesis, Mutagenesis, Impairment of Fertility.
On the contrary, beta adrenergic blockers may also potentiate the hypertensive response to withdrawal of clonidine in patients receiving concomitant clonidine and beta-adrenergic blocker. If a patient is treated with clonidine and Lopressor concurrently, and clonidine treatment is to be discontinued, stop Lopressor several days before clonidine is withdrawn. Rebound hypertension that can follow withdrawal of clonidine may be increased in patients receiving concurrent beta-blocker treatment. If signs or symptoms of heart failure develop, treat the generic Metoprolol No Rx according to recommended guidelines. It may be necessary to lower the dose of Lopressor or to discontinue it. Bradycardia Bradycardia, including sinus pause, heart block, Generic Metoprolol No Rx, and generic Metoprolol No Rx arrest have occurred with the use of Lopressor. Patients with first-degree atrioventricular block, sinus node dysfunction, or conduction disorders may be at increased risk.
Monitor heart rate and rhythm in patients receiving Lopressor. If severe bradycardia develops, reduce or stop Lopressor.
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Exacerbation Of Bronchospastic Disease Patients with bronchospastic disease, should, in www.cottoncandylover.com not receive beta blockers, including Lopressor. Because of its relative beta selectivity, however, Lopressor may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, generic Metoprolol No Rx antihypertensive treatment. Diabetes And Hypoglycemia Beta blockers may mask tachycardia occurring with hypoglycemia, but generic Metoprolol No Rx manifestations such as dizziness and sweating may not be significantly affected.
Pheochromocytoma If Lopressor is used in the setting of pheochromocytoma, it should be given in combination with an alpha blocker, and only after the alpha blocker has been initiated.